Liver function from Y to Z

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Liver function from Y to Z.

In the 1960s, my lab was interested in understanding how bilirubin and other organic anions are transferred from the plasma through the liver cell and into the bile. We performed gel filtration of liver supernatants and identified two protein fractions, designated Y and Z, which bound organic anions including bilirubin, and thus we proposed that they were involved in hepatic uptake of organic a...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2012

ISSN: 0021-9738

DOI: 10.1172/jci64587